Magnetic 3D Cell Culturing

Magnetic 3D Cell Culturing 

The core technology is the magnetization of cells with NanoShuttle™-PL. The cells can be aggregated with magnetic forces, either by levitation or printing, to form structurally and biologically representative 3D models in vitro.
 
The advantages of magnetic cell culture include:

  •         Mimicking native tissue environment
  •         Rapid 3D model formation within hours
  •         No specialized equipment, media, or artificial substrate
  •         Easy to handle / no sample loss
  •         Allows co-culture
With magnetized spheroids, solution addition and removal is made easy by using magnetic force to hold them in a stationary position during aspiration, thereby limiting spheroid loss. Spheroids can also be picked up and transferred between vessels using magnetic tools such as the MagPen™.

NanoShuttle™-PL consists of gold, iron oxide, and poly-L-lysine. NanoShuttle™-PL magnetizes cells by electrostatically attaching to cell membranes during an overnight static incubation. Magnetized cells will appear peppered with dark nanoparticles after incubation. NanoShuttle™-PL will stay attached to the cell membrane for up to 8 days, at which point it’s released into the 3D culture. NanoShuttle™-PL is biocompatible, having no effect on metabolism, proliferation, and inflammatory stress, and even encouraging proliferation in 3D. Additionally, it does not interfere with experimental techniques, such as fluorescence, or Western blotting.

Item: 655830

96 WELL DRIVES SPHEROID DRIVE, HOLDING DRIVE

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Item: 655837

96 WELL HOLDING DRIVE

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Item: 655841

96 WELL BIOPRINTING KIT, µCLEAR®, BLACK, NANOSHUTTLE, 600 µL, SPHEROID DRIVE, HOLDING DRIVE, 96 WELL MICROPLATE, CELL-REPELLENT SURFACE

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Item: 655846

96 WELL BIO ASSAY KIT, CLEAR, NANOSHUTTLE 600 µL, 6 WELL + 96 WELL DRIVES, 6 + 96 WELL MICROPLATES, CELL-REPELLENT, 96 WELL MASTERBLOCK

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Item: 655849

96 WELL BIO ASSAY KIT + IMAGING SYSTEM, NANOSHUTTLE 600 µL, 6 WELL + 96 WELL DRIVES, 6 + 96 WELL MICROPLATES, CELL-REPELLENT SURFACE, CLEAR, 96 WELL MASTERBLOCK, IMAGING SYSTEM, LIGHT PAD

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Item: 655850

96 WELL RING DRIVE

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Item: 657840

6 WELL BIO-ASSEMBLER KIT, CLEAR, NANOSHUTTLE 600 µL, LEVITATING DRIVE, HOLDING DRIVE, 6 WELL MICROPLATE, CELL-REPELLENT SURFACE

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Item: 657841

NANOSHUTTLE-PL, 1 VIAL (600 µL)

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Item: 657843

NANOSHUTTLE-PL, 3 VIALS (600 µL)

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Item: 657846

NANOSHUTTLE-PL, 6 VIALS (600 µL)

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Item: 657850

MAGPEN 3 PACK, TEFLON CAPS, MAGNETS

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Item: 657852

NANOSHUTTLE-PL, 12 VIALS, 600 µL

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Item: 657860

IMAGING KIT, IMAGING SYSTEM, 96 + 384 WELL IMAGING MASKS, LIGHT PAD, COOLING FAN

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Item: 657860-02

IMAGING KIT, IMAGING SYSTEM, 96 + 384 WELL IMAGING MASKS, LIGHT PAD, COOLING FAN

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Item: 662840

24 WELL BIO-ASSEMBLER KIT, CLEAR, NANOSHUTTLE 600 µL, LEVITATING DRIVE, HOLDING DRIVE, 24 WELL MICROPLATE, CELL-REPELLENT SURFACE

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Item: 781830

384 WELL DRIVES SPHEROID DRIVE, HOLDING DRIVE

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Item: 781835

384 WELL SPHEROID DRIVE

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Item: 781840

384 WELL BIOPRINTING KIT, CLEAR, NANOSHUTTLE 600 µL, SPHEROID DRIVE, HOLDING DRIVE, 384 WELL MICROPLATE, CELL-REPELLENT SURFACE

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Item: 781841

384 WELL BIOPRINTING KIT, µCLEAR®, BLACK, NANOSHUTTLE 600 µL, SPHEROID DRIVE, HOLDING DRIVE, 384 WELL MICROPLATE, CELL-REPELLENT SURFACE

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Item: 781846

384 WELL BIO ASSAY KIT, CLEAR, NANOSHUTTLE 600 µL, 6 WELL + 384 WELL DRIVES, 6 WELL + 384 WELL MICROPLATES, CELL-REPELLENT SURFACE, 96 WELL MASTERBLOCK

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Item: 781849

384 WELL BIO ASSAY KIT + IMAGING SYSTEM, NANOSHUTTLE 600 µL, 6 WELL + 384 WELL DRIVES, 6 WELL + 384 WELL MICROPLATES, CELL-REP. SURF., 96 WELL MASTERBLOCK, IMAG. SYS., LIGHT PAD

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Item: 781850

384 WELL RING DRIVE

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