Surfaces used in cell culture are generally designed for an optimal cell adherence. CELLSTAR® cell culture vessels with a cell-repellent surfaces have been developed to prevent cell attachment to the surface effectively. The product portfolio of Greiner Bio-One with non-binding surfaces includes dishes, plates, and flasks.
The ultra-low attachement surface products are by default sterile, non-cytotoxic, free of detectable endotoxins, detectable DNase / RNase and human DNA and have a shelf-life of 4 years.
Cell culture vessels with cell-repellent surface reliably prevent cell attachment in suspension cultures of semi adherent / adherent cell lines where standard hydrophobic surfaces generally used for suspension culture are insufficient.
A cell-repellent surface reliably prevents cell attachment in suspension cultures of semiadherent and adherent cell lines where standard hydrophobic surfaces generally used for suspension culture are insufficient.
Available as 6 / 12 / 24 and 48 well multiwell plates. Also available are the 96 and 384 well plates with various well geometries and optional µClear® film bottom.
Cell culture is an essential tool in drug discovery, tissue engineering, toxicology testing, stem cell research, as well as in basic research. Beside conventional two-dimensional (2D) monolayer cell culture, 3D cell culture models are becoming a routine tool which enables the expression of extracellular matrix (ECM) components as well as the formation of cell-cell and cell-matrix interactions. These characteristics are important for replicating in vivo cell differentiation, proliferation, and function in vitro. Cell culture vessels with cell-repellent surface are suitable for this purpose. These are also an ideal platform for long-term cultivation in hydrogels.
Applications for the ultra-low attachent surfaces:
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